A 76-year-old woman was previously suspected of having asthma at another hospital and was treated with an inhaled corticosteroid/long-acting β₂-agonist inhaler. However, her wheezing symptoms did not improve, and she presented for further evaluation. She has no history of smoking and no prior history of tuberculosis. Pulmonary function testing, bronchoscopy, fractional exhaled nitric oxide, blood eosinophil count, and chest computed tomography results are provided. 

What is the diagnosis for this patient?

A 22-year-old woman, who underwent hematopoietic stem cell transplantation for acute myeloid leukemia three months ago, presented with persistent cough. Her chest computed tomography and biopsy findings are shown.

Which medication is the appropriate treatment?

A 22-year-old woman presented with a several-month history of persistent cough. On chest auscultation, localized wheezing was heard only in the left upper lobe. Bronchoscopy and biopsy findings are shown.

What is the diagnosis?

A 71-year-old woman presented with persistent cough. Her chest X-ray (Figure A), chest computed tomography (Figure B), and biopsy findings (Figure C) are shown.

What is the appropriate treatment?

A 29-year-old man was referred due to abnormal findings on chest imaging. He has a 10 pack-year smoking history. His chest X-ray (Figure A), chest computed tomography (Figures B1 and B2), and lung biopsy findings (Figure C1: low magnification, Figure C2: high magnification) are as follows. Staining and culture of the lung tissue did not detect Mycobacterium tuberculosis or fungi.

What is the diagnosis?

A 37-year-old man was referred due to abnormal findings on chest imaging. He had been treated for pneumothorax 12 years ago and has a 17 pack-year smoking history. His chest X-ray (Figure A), chest computed tomography (Figures B1 and B2), and lung biopsy findings (Figure C1: low magnification, Figure C2: high magnification with special staining) are as follows.

What is the diagnosis?

A 45-year-old man presents with cough, sputum production, and shortness of breath that have persisted for several months. He is a nonsmoker. His chest X-ray (Figure A), chest computed tomography (Figures B1 and B2), paranasal sinus computed tomography (Figure C), and pulmonary function test results (Figure D) are as follows.

What is the appropriate treatment for this patient?